Computational Pathology @
The Netherlands Cancer Institute


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TEAM SCIENCE





Team science is a collaborative effort to address a scientific challenge that leverages the strengths and expertise of professionals trained in different fields. Although traditional single-investigator driven approaches are ideal for many scientific endeavours, coordinated teams of investigators with diverse skills and knowledge may be especially helpful for studies of complex problems with multiple causes [1]



Hugo Horlings



Clinical Group Leader



Curriculum Vitae

Email



Jonas Teuwen



Tenure Track Researcher



Personal Website

Email



Eric Marcus



Postdoctoral Fellow 2021



Email



Siamak Haijzadeh



Postdoctoral fellow 2019 -



Email



Rolf Harkes



Postdoctoral Fellow 2020



Email



Jan Hudecek



Software Engineer



Email



Tessa Steenbruggen



PhD Student 2017-2022



Email



Iris Nederlof



PhD Student 2017-2022



Email



Leonie voorwerk



PhD Student 2017-2022



Email



Lilian van wagensveld



PhD Student 2018-2022



Email



CEDRIC WALKER



PhD Student 2019-2023



Email



Yoni Schirris



PhD Student 2020-2024



Email



Andreas Panteli



PhD Student 2020-2024



Email



AjeH Karkala



PhD Student 2021-2025



Email



WE ARE INVOLVED IN THE FOLLOWING CONSORTIA



AACR GENIE





aims to catalyze sharing of integrated genomic and clinical datasets across multiple institutions worldwide, and thereby enable precision cancer medicine research, including the identification of novel therapeutic targets, design of biomarker-driven clinical trials, and identification of genomic determinants of response to therapy.


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N-CIA





This infrastructure initiative aims at providing a nationally accessible infrastructure for standardized analyses of a wide collection of parameters relevant to immune mediated tumour-control and therefore N-CIA will support the standardized sampling of tumour and blood of metastatic cancer patients.


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Immuno-oncology biomarker





The purpose of this Working Group is to develop, in a timely manner, standards on the assessment of Immuno-Oncology Biomarkers to aid pathologists, clinicians and researchers in their research and daily practice.


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AOCR





Our goal is to built a Dutch nationwide multidisciplinary platform (Archipelago of Ovarian Cancer Research; AOCR) to centralize and expand (pre)clinical and translational research for ovarian cancer to improve diagnosis, treatment and outcome of patients with ovarian cancer.


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OTTA





Is a forum of investigators of tumor studies of ovarian cancer, formed in April 2010. The aim of the group is to combine data from many studies, to provide a reliable assessment of the risks associated with specific ovarian tumor features.


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BIGPICTURE





The purpose of this Working Group is to develop, in a timely manner, standards on the assessment of Immuno-Oncology Biomarkers to aid pathologists, clinicians and researchers in their research and daily practice.


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ALUMNI



Robert Elens



2019 - BSC Hogeschool Holland





Maite Timmermans



2018 - Visiting PhD student
Currently Resident in Gynaecology





Lisanne Verhoef



2018 - MSc Student, LUMC
Currently PhD student UMC Amsterdam





Juliette van Baal



2018- Visiting PhD student
Currently Resident in Gynaecology





Lauri Borghuis



2018 - BSc Student, Saxion Hogeschool
Currently MsC student UMC Amsterdam





LISA WILLEMSE



2017- MsC Student Rene Bernards
Currently PhD student VUMC Amsterdam





WE ARE PERFORMING TRANSLATIONAL RESEARCH For THE FOLLOWING Clinical TRIALS


Tonic Trial

Nivolumab After Induction Treatment in Triple-negative Breast Cancer (TNBC) Patients


Bellini Trial

Pre-operative phase II basket trial for breast cancer immune special types with ipilimumab/nivolumab


Gelato Trial

AssessinG Efficacy of Carboplatin and ATezOlizumab in Metastatic Lobular Breast Cancer


OVI-HIPEC II

Secondary Debulking Surgery

+/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer


OVI-PEMBRO

Neo-adjuvant Pembrolizumab in Primary Stage IV Ovarian Cancer



Our Key National and International Collaborators



Local





Marleen Kok / Gabe Sonke

Willemien van Driel / Christianne Lok

Lodewyk Wessels / Ton Schumacher

Jacco van Reenen / Sven Rottenberg

Rene Bernards / Jos Jonkers



National





Evangalos / Estratios Gavves

Marc van de Vijver / Frederike Dijk

​Maaike van der Aa / Roy Kruithof

Francesco Compi / Jeroen van der Laak



interNational





Christina Curtis / Michael Angelo / Rob West

Michael Anglesio / David Huntsman

Christine Desmedt / Roberto Salgado

Laura van 't Veer / YinYin Yuang



HorlingsLab (c) 2019. All rights reserved. Design Hugo Horlings.